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Functional significance of histone deacetylase diversity

✍ Scribed by Saadi Khochbin; André Verdel; Claudie Lemercier; Daphné Seigneurin-Berny

Book ID: 117654751
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 78 KB
Volume: 11
Category: Article
ISSN: 0959-437X
DOI: 10.1016/s0959-437x(00)00174-x

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## Abstract Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from lysine residues in both histone and non‐histone proteins. They play a key role in the regulation of gene transcription and many other biological processes involving chromatin. Significantly, recent