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Functional polymorphisms of cyclooxygenase-2 (COX-2) gene and risk for urinary bladder cancer in North India

✍ Scribed by Ruchika Gangwar; Anil Mandhani; Rama Devi Mittal

Book ID
113921511
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
97 KB
Volume
149
Category
Article
ISSN
0039-6060

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## Abstract The mechanisms whereby cyclooxygenase‐2 (COX‐2) overexpression may contribute to bladder carcinogenesis remain unknown. We recently developed a transgenic mouse model overexpressing COX‐2 under the control of a bovine keratin 5 (BK5) promoter causing a high incidence of transitional cel