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Functional polymorphisms of cyclooxygenase-2 (COX-2) gene and risk for esophageal squmaous cell carcinoma

✍ Scribed by Rohit Upadhyay; Meenu Jain; Shaleen Kumar; Uday Chand Ghoshal; Balraj Mittal

Book ID: 113809279
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 358 KB
Volume: 663
Category: Article
ISSN: 0027-5107
DOI: 10.1016/j.mrfmmm.2009.01.007

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## Abstract Functional SNPs in the __COX‐2__ promoter region have been associated with susceptibility to esophageal squamous‐cell carcinoma (ESCC). In this study, we investigated SNPs in the __COX‐2__ coding region and their impact on risk of ESCC. The coding region of __COX‐2__ in DNAs from 30 Han