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Functional polymorphism of the NQO2 gene is associated with methamphetamine psychosis

✍ Scribed by Shintaro Ohgake; Kenji Hashimoto; Eiji Shimizu; Hiroki Koizumi; Naoe Okamura; Kaori Koike; Daisuke Matsuzawa; Yoshimoto Sekine; Toshiya Inada; Norio Ozaki; Nakao Iwata; Mutsuo Harano; Tokutaro Komiyama; Mitsuhiko Yamada; Ichiro Sora; Hiroshi Ujike; Yukihiko Shirayama; Masaomi Iyo

Book ID
111739787
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
55 KB
Volume
10
Category
Article
ISSN
1355-6215

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## Abstract Several lines of evidence suggest that oxidative stress plays a role in the mechanisms of action of methamphetamine (MAP) in the human brain. Given the role of glutathione __S__‐transferases (GSTs) in the protection against oxidative stress, genes encoding the GSTs have been considered