✍ Scribed by Josef Voříšek
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In living astrocytes and MDCK cells we observed morphological phenomena during and after heat shock (HS) utilizing our new perfusable microchamber system, which monitors pH, pO 2 , pCO 2 , and temperature. By means of electronic light microscopy and confocal laser scanning microscopy, mitochondria w
The expression of mammalian G protein coupled receptors (GPCRs) in S. cerevisiae provides a powerful assay system for functional analysis, ligand identi®cation and pharmaceutical screening. However, relatively few receptors have been coupled to the pheromone response pathway via the yeast G a , Gpa1
## Abstract This article focuses on β‐amyloid (Aβ) peptide production and secretion in the regulated secretory pathway and how this process relates to accumulation of toxic Aβ in Alzheimer's disease. New findings are presented demonstrating that most of the Aβ is produced and secreted, in an activi
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