## Cyclooxygenase -2 (COX-2), an inducible enzyme that catalyzes the formation of prostaglandins and other eicosanoids from arachidonic acid, is constitutively expressed in several human carcinomas. COX-2 expression, however, has not been extensively studied in leukemia. Human T cell leukemia virus
✦ LIBER ✦
Functional mapping of the activity of the R region in the human T-cell leukemia virus type I long terminal repeat to increase gene expression
✍ Scribed by Masataka Nakamura; Kiyoshi Ohtani; Yorio Hinuma; Kazuo Sugamura
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 532 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0920-8569
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## Abstract HTLV‐I is the etiologic agent of ATL and of tropical spastic paraparesis/HTLV‐I‐associated myelopathy. Infiltration of various tissues by circulating leukemic cells and HTLV‐I‐infected T cells is a characteristic of ATL and HTLV‐I‐associated inflammatory diseases. Chemokines play import