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Functional interaction between human papillomavirus type 18 E2 and poly(ADP-ribose) polymerase 1

✍ Scribed by Lee, Daeyoup; Kim, Jin Woo; Kim, Karam; Joe, Cheol O; Schreiber, Valérie; Ménissier-de Murcia, Josiane; Choe, Joonho


Book ID
110066883
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
272 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract The E2 protein of the papillomavirus plays an essential role in the viral life cycle. Through a yeast two‐hybrid screening, human polo‐like kinase 1 was found to interact with human papillomavirus type 5 E2. Further characterization identified that the domains responsible for the intera