Inherited mutations affecting the INK4a/ARF locus (CDKN2A) are associated with melanoma susceptibility in 40% of multiple case melanoma families. Over 60 different germline INK4a/ARF mutations have been detected in more than 190 families worldwide. The majority of these alterations are missense muta
Functional impairment of p16INK4A due to CDKN2A p.Gly23Asp missense mutation
✍ Scribed by Maria Chiara Scaini; Elisabetta Rossi; Paula Lobao Antunes de Siqueira Torres; Daniela Zullato; Monia Callegaro; Cinzia Casella; Monica Quaggio; Simona Agata; Sandro Malacrida; Vanna Chiarion-Sileni; Antonella Vecchiato; Mauro Alaibac; Marco Montagna; Graham J. Mann; Chiara Menin; Emma D’Andrea
- Book ID
- 113809360
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 672 KB
- Volume
- 671
- Category
- Article
- ISSN
- 0027-5107
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