Inherited mutations affecting the INK4a/ARF locus (CDKN2A) are associated with melanoma susceptibility in 40% of multiple case melanoma families. Over 60 different germline INK4a/ARF mutations have been detected in more than 190 families worldwide. The majority of these alterations are missense muta
Point mutations can inactivate in vitro and in vivo activities of p16INK4a/CDKN2A in human glioma
β Scribed by Arap, Wadih; Knudsen, Erik S; Wang, Jean YJ; Cavenee, Webster K; Huang, H-J Su
- Book ID
- 110060522
- Publisher
- Nature Publishing Group
- Year
- 1997
- Tongue
- English
- Weight
- 440 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0950-9232
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