Modification of fibrinogen with poly(eth
Modification of fibrinogen with poly(ethylene glycol) and its effects on fibrin clot characteristics
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Barker, T. H. ;Fuller, G. M. ;Klinger, M. M. ;Feldman, D. S. ;Hagood, J. S.
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Article
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2001
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John Wiley and Sons
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English
β 208 KB
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The suitability of existing topical fibrin glue preparations for tissue sealing or local drug delivery applications is greatly limited by their poor mechanical properties and the limited capacity of fibrinogen (Fgn) to actively bind growth factors or other therapeutic agents. Poly(ethylene glycol) (