✦ LIBER ✦

Functional Imaging by I0- and T2* -parameter mapping using multi-image EPI

✍ Scribed by Dr. Oliver Speck; Jürgen Hennig

Book ID: 102952640
Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 747 KB
Volume: 40
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910400210

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✦ Synopsis

Abstract

A new functional imaging method has been developed and used to measure T~2~*‐ and initial intensity (I~0~)‐parameter maps of multiple slices during activation of the cortex with high temporal resolution. Multiple echo‐planar images (EPls) are read out after a single excitation of the spin system, leading to several images with increasing effective echo times. Changes induced by primary visual stimulation in T~2~* and I~0~ were measured in eight subjects. Although stimulation‐induced increases in I~0~ only occurred at short repetition times, T~2~* increased from 57.3 to 60.9 ms on average. The method combines the high stability of a single shot EPI experiment with the high information content of a multiecho acquisition. In addition, stimulation‐induced changes in inflow can be easily separated from true blood oxygenation level dependent (BOLD) signal changes.

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