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Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility

✍ Scribed by Zhou, Y.

Book ID
126450933
Publisher
Oxford University Press
Year
2005
Tongue
English
Weight
82 KB
Volume
26
Category
Article
ISSN
0143-3334

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## Abstract Matrix metalloproteinases (MMPs) play an important role in several steps of cancer development. A single guanine insertion polymorphism (2G) in the __MMP1__ promoter sequence at βˆ’1,607 creates an Ets binding site and thus results in enhancing transcriptional activity. This study aimed t