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Functional ‘glial’ GLYT1 glycine transporters expressed in neurons

✍ Scribed by Luca Raiteri; Maurizio Raiteri

Book ID
111184060
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
173 KB
Volume
114
Category
Article
ISSN
0022-3042

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Neuronal dependency of the glycine trans
Neuronal dependency of the glycine transporter GLYT1 expression in glial cells
✍ Francisco Zafra; Irene Poyatos; Cecilio Gimenez 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 364 KB

Two membrane-localized transporter proteins (GLYT1 and GLYT2) are responsible for removal of extracellular glycine in the mammalian CNS. Whereas GLYT1 seems to be expressed mainly in glial cells, GLYT2 is neuronal. The highest concentrations of both transporters are found in glycinergic areas of the