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Functional expression of ribozymes in Apicomplexa: Towards exogenous control of gene expression by inducible RNA-cleavage

โœ Scribed by Carolina Agop-Nersesian; Judith Pfahler; Michael Lanzer; Markus Meissner

Book ID
113654735
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
314 KB
Volume
38
Category
Article
ISSN
0020-7519

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We have established a gene regulatory system in mice by the inducible anti-sense RNA. We have generated transgenic mice carrying the anti-sense DNA composed of the class II MHC gene under the control of the human metallothionein IIa gene promoter. The detectable amount of anti-sense RNA was constitu