Functional expression of P-glycoprotein in the hepatic canalicular membrane of developing rats
β Scribed by Amrita V. Kamath; Marilyn E. Morris
- Book ID
- 109388923
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 72 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0022-3549
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To study the effect of bile acids on P-glycoproteinmediated drug transport, we performed experiments using multidrug resistant cells and rat canalicular membrane vesicles. Cellular accumulation and efflux of rhodamine 123 were measured in drug-resistant cells by means of computerized quantitative im