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Functional expression of CD80 and CD86 allows immunogenicity of malignant B cells from non-Hodgkin’s lymphomas

✍ Scribed by Laurence Chaperot; Joël Plumas; Marie-Christine Jacob; Frédérique Bost; Jean-Paul Molens; Jean-Jacques Sotto; Jean-Claude Bensa


Book ID
114217311
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
456 KB
Volume
27
Category
Article
ISSN
0301-472X

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The c-kit proto-oncogen (CD117) has been described to be present in normal and neoplastic hemopoietic cells including both myeloid and lymphoid lineages. Among the normal lymphoid cells CD117 expression would be restricted to a small subset of NKcells, and to early T-cell precursors and it is not ex