CD45 is a glycoprotein expressed in all lymphohemopoietic cells. Its expression increases during B-lymphocyte ontogeny. Few data are available about CD45 expression in the various types of low-grade B-cell non-Hodgkin's lymphomas (NHL). Low levels of CD45 have been reported in pathologic lymphocytes
β¦ LIBER β¦
Expression of the low Mr isoform of CD45 (CD45RO) in B-cell non-Hodgkin's lymphomas
β Scribed by Charles W. Caldwell; Lucinda M. Marty; Thomas L. Feldbush
- Book ID
- 118375361
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 587 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1090-2341
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CD40 is a membrane glycoprotein expressed on normal and neoplastic B lymphocytes. Stimulation through CD40 regulates important cellular functions, but the effects depend on its membrane density. While extensive studies have characterized CD40 in non-Hodgkin lymphomas of immunocompetent individuals,