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Functional expression of Ca2+ signaling pathways in mouse embryonic stem cells

โœ Scribed by Eri Yanagida; Satoshi Shoji; Yoshiyuki Hirayama; Fumio Yoshikawa; Keishi Otsu; Hiroshi Uematsu; Masayasu Hiraoka; Teiichi Furuichi; Seiko Kawano

Book ID
113525378
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
480 KB
Volume
36
Category
Article
ISSN
0143-4160

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Retinoic acid (RA) induces the differentiation of murine embryonic stem (ES) cells to cell types resembling those found in the early embryo. When cultured in the presence of leukemia inhibitory factor (LIF), ES cells are maintained in an undifferentiated (self-renewing) state. Addition of RA to the