Signaling pathways regulating proliferation of mouse embryonic stem cells
β Scribed by I. A. Chuykin; M. S. Lianguzova; V. A. Pospelov
- Book ID
- 111471393
- Publisher
- Pleiades Publishing
- Year
- 2007
- Tongue
- English
- Weight
- 283 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1990-519X
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Retinoic acid (RA) induces the differentiation of murine embryonic stem (ES) cells to cell types resembling those found in the early embryo. When cultured in the presence of leukemia inhibitory factor (LIF), ES cells are maintained in an undifferentiated (self-renewing) state. Addition of RA to the
## Abstract Spermatogenesis is the process that involves the division and differentiation of spermatogonial stem cells (SSCs) into mature spermatozoa. SSCs are a subpopulation of type A spermatogonia resting on the basement membrane in the mammalian testis. Selfβrenewal and differentiation of SSCs