Functional expression of a microinjected Edα gene in C57BL/6 transgenic mice
✍ Scribed by Yamamura, Ken-ichi; Kikutani, Hitoshi; Folsom, Virginia; Clayton, Linda K.; Kimoto, Masao; Akira, Shizuo; Kashiwamura, Shin-ichiro; Tonegawa, Susumu; Kishimoto, Tadamitsu
- Book ID
- 109739537
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 375 KB
- Volume
- 316
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/316067a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We have established a strain of transgenic mice in which the HLA-DRA gene was integrated into the Xchromosome and the xenogeneic mixed isotype molecule, DR~E/3 b, was expressed in a cell type-specific manner, although the transgenie DRA gene contained only 268 base pairs of the 5'-flanking region. T
## Abstract Numerous transgenic mouse models for Alzheimer's disease (AD) have been generated to recapitulate the histological pathogenesis and behavioral phenotypes of AD brain. However, none of the existing models exhibits the full spectrum of AD symptoms, nor have all of the traits mimicked by t