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Functional effects of a tandem duplication polymorphism in the 5′flanking region of the DRD4 gene

✍ Scribed by Ursula M. D’Souza; Carsten Russ; Eda Tahir; Jonathan Mill; Peter McGuffin; Philip J. Asherson; Ian W. Craig


Book ID
119196507
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
223 KB
Volume
56
Category
Article
ISSN
0006-3223

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The dopamine D4 receptor (DRD4) is a member of the D2-like dopamine receptor family. Polymorphisms at the DRD4 gene have been examined for association with a wide range of neuropsychiatric disorders and normal behavioral variation. The DRD4 gene is unusual in its high amount of expressed polymorphis