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Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations

โœ Scribed by J. Weng; W. M. Macfarlane; M. Lehto; H. F. Gu; L. M. Shepherd; S. A. Ivarsson; L. Wibell; T. Smith; L. C. Groop


Book ID
105822441
Publisher
Springer
Year
2001
Tongue
English
Weight
275 KB
Volume
44
Category
Article
ISSN
0012-186X

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Maturity onset diabetes of the young (MODY) is a genetically heterogeneous form of type 2 diabetes that is characterized by autosomal dominant inheritance, onset in early adulthood and a primary defect in insulin secretion. Mutations in at least six genes have been shown to underlie MODY, including