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Functional consequences of mutations in the autophagy genes in the pathogenesis of Crohn's disease

✍ Scribed by Oliver Brain; Rachel Cooney; Alison Simmons; Derek Jewell

Book ID
112101171
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
715 KB
Volume
18
Category
Article
ISSN
1078-0998

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## Background: The autophagy pathway has been linked with Crohn's disease (CD) through association of the ATG16L1 and IRGM genes with susceptibility for CD, and also to the Nod2 pathway, involved in CD. Our aim was to investigate polymorphisms in selected autophagy genes for their association with