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Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells

✍ Scribed by Bucchi, Annalisa; DiFrancesco, Dario; Robinson, Richard; Qu, Jihong; Altomare, Claudia

Book ID
113041840
Publisher
Springer
Year
2002
Tongue
English
Weight
87 KB
Volume
444
Category
Article
ISSN
0031-6768

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✍ Arne Battefeld; Claudia Bierwirth; Ying Chuan Li; Lennart Barthel; Tanja Velmans 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 706 KB

## Abstract Hyperpolarization‐activated cyclic nucleotide‐gated ion channels (HCN) are key determinants of CNS functions. Here we describe an increase in hyperpolarization‐activated current (__I__~h~) at the beginning of whole‐cell recordings in rat layer 5 cortical neurons. For a closer investigat