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Functional characterization of NK1.1+ Ly-6C+ cells

✍ Scribed by Naoko Sato; Takashi Yahata; Kazuki Santa; Akio Ohta; Yasushi Ohmi; Sonoko Habu; Takashi Nishimura


Book ID
108408483
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
472 KB
Volume
54
Category
Article
ISSN
0165-2478

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We previously reported and partially characterized a unique monoclonal antibody (mAb), U5A2-13, which recognizes a T cell subset similar to NK1.1 + T cells, not only in NK1.1positive mouse strains but also in NK1.1-negative strains. In NK1.1-positive C57BL/6 mice, U5A2-13 + TCR Β§ g + cells produced

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## Abstract A novel receptor, named 1C7 or NKp30 and involved in natural cytotoxicity, was recently identified. This receptor is encoded by the __1C7__ gene, which is located within the class III region of the human MHC, __HLA__. It is a member of the immunoglobulin gene superfamily (IgSF) and, rem