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Functional characterization of neurokinin receptors with agonists and antagonists

✍ Scribed by D. Regoli; Q.T. Nguyen; D. Jukic; N. Rouissi


Book ID
119117824
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
143 KB
Volume
46
Category
Article
ISSN
0167-0115

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The neurokinin-1 (NK-1, substance P) receptor belongs to the class of seven transmembrane domain (7-TM) receptors that interact with cellular effector systems via guanine nucleotide binding regulatory proteins (G-proteins). In this study, coupling mechanisms of functional NK-1 receptoirs endogenousl