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Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells

โœ Scribed by R H P Porter; K R Benwell; H Lamb; C S Malcolm; N H Allen; D F Revell; D R Adams; M J Sheardown


Book ID
110004494
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
242 KB
Volume
128
Category
Article
ISSN
0007-1188

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ChemInform Abstract: Simplified Analogue
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Simplified Analogues of Ritanserin and Their Affinity at 5-HT 2A , 5-HT 2B , and 5-HT 2C Serotonin Receptors. -A variety of derivatives of 4-[bis(4-fluorophenyl)methylene]piperidine (I) are synthesized and evaluated for their affinity at 5-HT serotonin receptors. The compounds (I) show lower binding