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Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line

โœ Scribed by Yohko Nakamura; Toshinori Ozaki; Hidetaka Niizuma; Miki Ohira; Takehiko Kamijo; Akira Nakagawara


Book ID
116294332
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
567 KB
Volume
354
Category
Article
ISSN
0006-291X

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Homozygous deletion in a neuroblastoma c
โœ Ying Zhang Chen; Eiichi Soeda; Hong Wei Yang; Junko Takita; Ling Chai; Akira Hor ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB

## Abstract Recent molecular studies have shown a relatively high rate of loss of heterozygosity (LOH) in neuroblastoma (NB) as well as other types of tumors in human chromosome band 1p36. To identify candidate tumor suppressor genes in NB, we searched for homozygous deletions in NB cell lines with