## Abstract A prominent role for the execution of cell cycle and growth regulatory mechanisms within the threeβdimensional context of nuclear architecture is becoming increasingly evident. Signaling pathways and regulatory networks that govern activation and suppression of genes controlling prolife
Functional capabilities of molecular network components controlling the mammalian G1/S cell cycle phase transition
β Scribed by Kohn, Kurt W
- Book ID
- 110061165
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 453 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Genetic intervention in cell-cycle regulation is a promising strategy to obtain mammalian cell culture proliferation in the absence of exogenous growth factors. In order to gain insights into this approach, known interactions among the four proteins cyclin E, cdk2, the retinoblastoma gene produ
A mathematical model of regulation of the G1-S transition of the mammalian cell cycle has been formulated to organize available experimental molecular-level information in a systematic quantitative framework and to evaluate the ability of this manifestation of current knowledge to calculate correctl
The histone gene is a paradigm for transcriptional control at the G1/S phase transition point in the cell cycle. The histone gene promoter provides a blueprint for integration of regulatory signals which mediate responsiveness to factors controlling competency for cell cycle progression at the initi