A monoclonal antibody with a high affinity for digitoxin (KA = 0.50 nM) and digoxin (KA = 0.55 nM) was produced by somatic cell fusion. This antibody, designated 2A3(47), displayed little cross reactivity with other glycosides. In cultured rat heart myocytes, 2A3(47), antagonized the positive chrono
β¦ LIBER β¦
Functional antagonism by monoclonal antibody to digoxin in the guinea-pig atria
β Scribed by Pancras C. Wong; Thomas M. Reilly; Robin A. Karol; Pieter B.M.W.M. Timmermans
- Book ID
- 115880731
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 255 KB
- Volume
- 136
- Category
- Article
- ISSN
- 0014-2999
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