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Functional analysis of a novel human serotonin transporter gene promoter in immortalized raphe cells

✍ Scribed by Ole V Mortensen; Mads Thomassen; Mads B Larsen; Scott R Whittemore; Ove Wiborg

Book ID
117387313
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
917 KB
Volume
68
Category
Article
ISSN
0169-328X

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Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizophrenia
✍ de Oliveira, JoοΏ½o R. Mendes; Otto, Paulo A.; Vallada, Homero; Lauriano, ValοΏ½ria; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 11 KB πŸ‘ 2 views

It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)