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A novel allele in the promoter region of the human serotonin transporter gene

✍ Scribed by Michaelovsky, E; Frisch, A; Rockah, R; Peleg, L; Magal, N; Shohat, M; Weizman, R

Book ID
110058956
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
52 KB
Volume
4
Category
Article
ISSN
1359-4184

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The human serotonin transporter (5-HTT), encoded by a single gene on chromosome 17q11.2, is expressed in brain and blood cells. 5-HTT is implicated in mood and anxiety regulation, and is where antidepressant and antianxiety drugs initially act in the brain. A 5-HTT-linked promoter region (5-HTTLPR)