Functional activity of T and B cells of the spleen during tumor growth
β Scribed by A. Sh. Norimov; R. M. Khaitov; S. S. Gambarov
- Publisher
- Springer US
- Year
- 1976
- Tongue
- English
- Weight
- 219 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0007-4888
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Spleen cells of BALB/c mice that had been inoculated with syngeneic plasmacytoma MOPC 104E were cultured for 11 days in T-cell growth factor (TCGF) and ultrasonicated tumor extract (USE). Cultured lymphocytes (MOPC-CL) possessed three-fold more lytic units than normal spleen cells cultured in TCGF w
## Abstract Spleens from LAF~1~ mice injected intravenously with sheep erythrocytes (SE) are relatively rich in memory T cells early in the immune response (1 to 3 days) and rich in memory B cells as the response progresses (2 weeks or more). Marked cooperation for the secondary immune response __i