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Function Induced Modifications of Gene Expression: an Alternative Approach to Gene Therapy of Duchenne Muscular Dystrophy

✍ Scribed by Gerta Vrbová

Book ID
111597126
Publisher
Springer Netherlands
Year
2004
Tongue
English
Weight
89 KB
Volume
25
Category
Article
ISSN
0142-4319

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✍ Makoto Ikezawa; Ichizo Nishino; Yu-ichi Goto; Teruhisa Miike; Ikuya Nonaka 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 25 KB 👁 2 views

A boy with the clinical phenotype of Duchenne muscular dystrophy had no detectable deletion or duplication in the dystrophin gene by the routine multiplex PCR method. In mRNA extracted from his muscle biopsy, newly recognized extra-exons of 172 bp and 202 bp were present between exon 25 and 26 sugge