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Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancer

โœ Scribed by N.A. Alam; S. Olpin; I.M. Leigh


Book ID
108668245
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
90 KB
Volume
153
Category
Article
ISSN
0007-0963

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## Abstract Recently, germline mutations of the fumarate hydratase (__FH__) gene, in 1q42.1, have been found to be involved in syndromes associated with uterine leiomyomas (ULs). Compelling evidence also supports a genetic liability to develop nonsyndromic UL, although susceptibility genes have not