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Downregulation of SRF–FOS–JUNB pathway in fumarate hydratase deficiency and in uterine leiomyomas

✍ Scribed by Raimundo, N; Vanharanta, S; Aaltonen, L A; Hovatta, I; Suomalainen, A


Book ID
109970806
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
545 KB
Volume
28
Category
Article
ISSN
0950-9232

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✍ Karen L. Gross; Carolien I. M. Panhuysen; Michael S. Kleinman; Hilary Goldhammer 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB

## Abstract Recently, germline mutations of the fumarate hydratase (__FH__) gene, in 1q42.1, have been found to be involved in syndromes associated with uterine leiomyomas (ULs). Compelling evidence also supports a genetic liability to develop nonsyndromic UL, although susceptibility genes have not