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โœฆ   LIBER   โœฆ

Fulminant epstein-barr viral hepatitis: Orthotopic liver transplantation and review of the literature

โœ Scribed by Feranchak, Andrew P. ;Tyson, R. Weslie ;Narkewicz, Michael R. ;Karrer, Frederick M. ;Sokol, Ronald J.


Publisher
Wiley (John Wiley & Sons)
Year
1998
Tongue
English
Weight
623 KB
Volume
4
Category
Article
ISSN
1074-3022

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โœฆ Synopsis


Acute hepatic failure caused by primary Epstein-Barr virus (EBV) infection has been reported in the literature in 16 cases, with an overall mortality of 87%. We report a case of fulminant hepatic failure in an immunocompetent young girl caused by primary EBV infection that was treated by orthotopic liver transplantation. After transplantation she has been treated with low-dose immuno-suppression, a pooled gammaglobulin preparation containing anti-EBV antibodies, and anti-viral therapy. The patient is presently doing well 2 years after transplantation without evidence of clinical EBV infection, primary immunodeficiency, or lymphoproliferative disease.


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