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Fullerenol C60(OH)24 prevents doxorubicin-induced acute cardiotoxicity in rats

✍ Scribed by Torres, Vukosava Milic; Srdjenovic, Branislava; Jacevic, Vesna; Dragojevic Simic, Viktorija; Djordjevic, Aleksandar; Simplício, Ana Luísa


Book ID
122334443
Publisher
Elsevier
Year
2010
Tongue
English
Weight
384 KB
Volume
62
Category
Article
ISSN
1734-1140

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The effects of fullerenol C 60 (OH) 24 (Frl) at doses of 25, 50, and 100 mg/kg/week (for a time-span of 3 weeks) on heart and liver tissue after doxorubicin (Dox)-induced toxicity in rats with colorectal cancer were investigated. In the present study, we used an in vivo Wistar male rat model to expl