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FTY720-Induced Conversion of Conventional Foxp3−CD4+ T Cells to Foxp3+ Regulatory T Cells in NOD Mice

✍ Scribed by Yun Sun; Wenjing Wang; Bin Shan; Jingfang Di; Linlin Chen; Lingling Ren; Weiping Li; Da-Jin Li; Yi Lin


Book ID
111270489
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
703 KB
Volume
66
Category
Article
ISSN
8755-8920

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a