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FTY720 blocks allograft rejection by homing of lymphocytes in vivo

✍ Scribed by K Yuzawa; S.M Stephkowski; M Wang; B.D Kahan

Book ID: 117238842
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 49 KB
Volume: 32
Category: Article
ISSN: 0041-1345
DOI: 10.1016/s0041-1345(99)00953-7

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## Abstract This study was performed to observe the long‐term effect of FTY720 on lymphocyte count change and islet allograft survival. Diabetic C57BL/6 mice were given FTY720 (group 1, 0.5 mg/kg/day; group 2, 1.0 mg/kg/day) or its vehicle (group 3, controls) after transplantation. Median graft sur