From α-Amino Acids to Peptides: All You Need for the Journey.
✍ Scribed by Carmen Najera
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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📜 SIMILAR VOLUMES
N-Methyl b-amino acids are generally required for application in the synthesis of potentially bioactive modified peptides and other oligomers. Previous work highlighted the reductive cleavage of 1,3-oxazolidin-5-ones to synthesise N-methyl a-amino acids. Starting from a-amino acids, two approaches w
The reactions of enolizable carbonyl compounds with azomethine functions, usually referred to as Mannich-type reactions (also termed aza ± aldol reactions), result in the formation of b-amino acids, ketones, or aldehydes. [1] These reactions are conceptually equivalent to the aldol reactions, but, i
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