𝔖 Bobbio Scriptorium
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From sea urchins and sea squirts to man—Evolution of the extracellular matrix


Book ID
116729612
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
71 KB
Volume
26
Category
Article
ISSN
0945-053X

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## Abstract Previous investigations have demonstrated that differentiation in vitro of micromeres from sea urchin embryos requires the presence of serum. In this report we demonstrate that differentiation of micromeres, as judged by their ability to form spicules, will occur in the absence of serum

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A new embryonic extracellular matrix protein has been purified from eggs of the sea urchin Paracentrotus lividus. The molecule is a 210 kD dimer consisting of two 105 kD subunits that are held together by S-S bridges. In the unfertilized egg, the protein is found within granules uniformly distribute