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From interception to incorporation: degeneracy and promiscuous recognition as precursors of a paradigm shift in immunology

โœ Scribed by Ohad Parnes


Book ID
116755268
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
89 KB
Volume
40
Category
Article
ISSN
0161-5890

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Whenever hydrogen bonding is involved in molecular recognition, the possibility of a proton transfer from the donor to the acceptor arises. In most cases the pK a of the donor is far enough above the pK a of the conjugate acid of the acceptor for it to be clear that no proton transfer will occur. Ho