From gene to phenotype: Modelling the glucose-stimulated insulin secretion system
β Scribed by J.M. Hancock; L. Hazelwood; C. Ainali; M. Simon; M. Goldsworthy; R. Milton; R.D. Cox; M. Duchen
- Publisher
- Elsevier
- Year
- 2010
- Tongue
- English
- Weight
- 60 KB
- Volume
- 27
- Category
- Article
- ISSN
- 1871-6784
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β¦ Synopsis
The aim of the EnCORE project is to integrate across different database resources and analysis tools in a computationally accessible and extensible manner, facilitating automated with a special focus on systems biology. The EnCORE platform is available as a collection of webservices easy to integrate in data analysis workflows.
Building on EnCore, EnVision provides a graphical user interface for set-oriented data analysis integrating multiple data types such as protein sequences, molecular interactions, pathways, and systems biology models. We will demonstrate the current EnVision tool and describe the underlying concept of using community standards such as DAS to provide a stable and maintainable integrative data resource. http://www.ebi.ac.uk/enfin-srv/envision2/.
π SIMILAR VOLUMES
A mathematical model of the insulin}glucose feedback regulation in man is used to examine the e!ects of an oscillatory supply of insulin compared to a constant supply at the same average rate. We show that interactions between the oscillatory insulin supply and the receptor dynamics can be of minute