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Friedlaender Condensation of 5-Aminopyrazole-4-carbaldehydes with Reactive α-Methylene Ketones: Synthesis of Pyrazolo[3,4-b]pyridines.

✍ Scribed by Madhukar N. Jachak; Appasaheb B. Avhale; Chanda D. Tantak; Raghunath B. Toche


Publisher
John Wiley and Sons
Year
2006
Weight
40 KB
Volume
37
Category
Article
ISSN
0931-7597

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Reaction of 5-Aminopyrazoles with β-Dimethylaminopropiophenones. Synthesis of New Pyrazolo [3,4-b]pyridines. -Reaction of 5aminopyrazoles (I) with β-aminopropiophenones (II) provides a new and simple synthetic entry into the pyrazolo[3,4-b]pyridine ring system. Oxidation of the dihydro-products (II