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ChemInform Abstract: Reaction of 5-Aminopyrazoles with β-Dimethylaminopropiophenones. Synthesis of New Pyrazolo[3,4-b]pyridines.

✍ Scribed by J. QUIROGA; B. INSUASTY; S. CRUZ; P. HERNANDEZ; A. BOLANOS; R. MORENO; A. HORMAZA; R. H. DE ALMEIDA S.


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Reaction of 5-Aminopyrazoles with β-Dimethylaminopropiophenones. Synthesis of New Pyrazolo [3,4-b]pyridines.

-Reaction of 5aminopyrazoles (I) with β-aminopropiophenones (II) provides a new and simple synthetic entry into the pyrazolo[3,4-b]pyridine ring system. Oxidation of the dihydro-products (III) with NBS gives the completely aromatized compounds of type (IV). The reaction mechanism of the product formation is discussed.


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