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Frequent occurrence of in vivo clonal expansion of CD4− CD8− T cells bearing T cell receptor αβ chains in adult humans

✍ Scribed by Yoichiro Kusunoki; Yuko Hirai; Tomonori Hayashi; Seishi Kyoizumi; Keiko Takahashi; Yukari Morishita; Yoshiaki Kodama; Mitoshi Akiyama


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
611 KB
Volume
23
Category
Article
ISSN
0014-2980

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Expression of CD4 or CD8 on the cell surface is an important guide for discriminating the immunologic functions of T-cells. However, a minor T-cell subset lacking both CD4 and CD8 molecules but bearing the usual form of T-cell receptor (TCR)-alpha beta (CD4-CD8-TCR-alpha beta+ T-cells) has recently