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Frequent Loss of 1p32 Region but no Mutation if the p18 Tumor Suppressor Gene in Meningiomas

✍ Scribed by Pascal Leuraud; Yannick Marie; Eric Robin; Stéphanie Huguet; Jié He; Karima Mokhtari; Philippe Cornu; Khê Hoang-Xuan; Marc Sanson


Book ID
110235009
Publisher
Springer US
Year
2000
Tongue
English
Weight
67 KB
Volume
50
Category
Article
ISSN
0167-594X

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Deletion of the p53 tumor suppressor gen
✍ Gregor Tomasevic; Ramesh Raghupathi; Uwe Scherbel; Tadeusz Wieloch; Tracy K. McI 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 292 KB

## Abstract Deletion of the tumor suppressor gene p53 has been shown to improve the outcome in experimental models of focal cerebral ischemia and kainate‐induced seizures. To evaluate the potential role of p53 in traumatic brain injury, genetically modified mice lacking a functional p53 gene (p53^–