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Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers

✍ Scribed by Taniguchi, Hiroaki; Yamamoto, Hiroyuki; Hirata, Tamaki; Miyamoto, Nobuki; Oki, Mariko; Nosho, Katsuhiko; Adachi, Yasushi; Endo, Takao; Imai, Kohzoh; Shinomura, Yasuhisa

Book ID
110069952
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
327 KB
Volume
24
Category
Article
ISSN
0950-9232

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## Abstract The retinoblastoma protein‐interacting zinc finger gene, __RIZ1__ (GenBank accession number U17838), is involved in chromatin‐mediated gene expression and is also a target for frameshift mutation in microsatellite‐unstable cancers. Methylation of the __RIZ1__ promoter CpG island has bee