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Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancer

โœ Scribed by Nojima, M; Suzuki, H; Toyota, M; Watanabe, Y; Maruyama, R; Sasaki, S; Sasaki, Y; Mita, H; Nishikawa, N; Yamaguchi, K


Book ID
110072257
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
482 KB
Volume
26
Category
Article
ISSN
0950-9232

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Frequent epigenetic inactivation of hSRB
โœ Jin-Hee Lee; Do-Sun Byun; Min-Goo Lee; Byung-Kyu Ryu; Min-Ju Kang; Kwon-Seok Cha ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 970 KB

## Abstract __hSRBC__ is a putative tumor suppressor located at 11p15.4, at which frequent genomic loss has been observed in several human malignancies. To explore the candidacy of __hSRBC__ as a suppressor of gastric tumorigenesis, we analyzed the expression and mutation status of __hSRBC__ in gas